Head of Rare Genetic Disease Biology (Reading)


: $94,360.00 - $141,170.00 /year *

Employment Type

: Full-Time


: Scientific Research

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Agios (agios.com) is a biopharmaceutical company committed to applying our scientific leadership in cellular metabolism to transform the lives of patients with cancer and rare genetic diseases. We are growing rapidly with an active research and discovery pipeline across both therapeutic areas. Agios has two approved oncology precision medicines and multiple first-in-class investigational therapies in clinical and/or preclinical development.

As the leader for Rare Genetic Disease (RGD) biology at Agios, this role will play a substantial strategic role in guiding the scientific direction of Agios RGD portfolio which emphasizes innovative first-in-class therapies for inborn errors of metabolism. We are seeking an innovative and agile leader who brings significant expertise in disease biology as well as a passion for professional development and coaching.

Key Responsibilities

  • Refines and advances Agios RGD strategy. Sets and advocates future directions for Agios RGD research and ensures successful execution of leading-edge approaches to identify and prosecute novel therapeutic strategies
  • Ensures delivery of a robust pipeline of high-value, high-confidence programs spanning from Project/Target selection through Drug Discovery to Development Candidate nomination
  • Creative and scientifically-oriented leader who stays close to the science and drives data-driven decisions
  • Guides and supports the efforts of several interconnected teams of biologists, including drug discovery biology teams and teams focused on identification and validation of novel RGD targets
  • Propagates a development-oriented culture & champions the growth of a talented and aspirational team of RGD biologists
  • Maintains high-functioning and synergistic cross-functional relationships across the Agios discovery organization
  • Stays informed on trends and emerging developments regarding research and development in RGD
  • Communicates science and strategy effectively in a variety of internal and external settings


  • Ph.D. in biology or related field with 10-15+ years of industry experience
  • Demonstrated success in all phases of drug discovery, with a track record of successful advancement of novel, first-in-class therapeutics
  • Expertise and track record of scientific leadership in orphan genetic diseases preferably inborn errors of metabolism. Scientists with expertise in related biologic areas (such as metabolic disorders or neurosciences) will also be considered
  • Demonstrated success in managing and mentoring a diverse set of biology scientists
  • Demonstrated ability and commitment to building, guiding, and participating in effective teams and fostering productive internal collaborations
  • Excellent verbal and written communication and interpersonal skills to work across functions and within external collaborations, and a demonstrated ability to organize and communicate complex data sets in a clear and concise manner to cross-functional audiences
  • Experience in strategic planning, project leadership, and laboratory and budget management in a matrixed organization
  • Strong organizational and time-management skills and demonstrated ability to lead complex cross-functional collaborations including managing relationships with academic collaborators and CROs
  • Desire and capacity to participate in a dynamic and fast-paced research setting
  • Recognized scientific innovation and accomplishment evidenced by strong record of publication and conference presentations in RGD biology

Associated topics: biochemistry, bioinformatic, biology, biomechanics, biomedical engineer, biosynthetic, fermentation, neuro, pain, therapeutic * The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.

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